25526-94-7

Synonym(s):
3′-Chloro-3′-deoxythymidine

CAS NO.：25526-94-7

Empirical Formula: C10H13ClN2O4

Molecular Weight: 260.67

MDL number:

PRODUCT Properties

• Melting point: 180-182 °C
• Density: 1.48±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 9.55±0.10(Predicted)
• Major Application: pharmaceutical (small molecule)
• InChI: 1S/C10H13ClN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
• InChIKey: KQVJDKGDGLWBQT-SPDVFEMOSA-N
• SMILES: Cl[C@@H]1[C@H](O[C@H](C1)[n]2[c]([nH][c](c(c2)C)=O)=O)CO

Description and Uses

3''-Chloro-3''-deoxythymidine (Zidovudine EP Impurity B) is an impurity of 3''-Azido-3''-deoxythymidine (A825000), a potent and selective inhibitor of HIV-1 replication and a potential antiviral agent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302;H315;H319;H335
• Precautionary statements: P261;P305+P351+P338
• WGK Germany: WGK 3
• HS Code: 2934990002
• Storage Class: 11 - Combustible Solids