(2R)-2-((tert-butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)aceticacid , 1334321-39-9

CAS NO.：1334321-39-9

Empirical Formula: C17H27NO5

Molecular Weight: 325.4

MDL number: MFCD16621100

Pack Size	Price	Stock	Quantity
5g	RMB1148.00	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	>280°C (dec.)
Boiling point:	497.3±20.0 °C(Predicted)
Density	1.296±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	3.93±0.10(Predicted)
form	Solid
color	White to Off-White

Description and Uses

Boc-3-hydroxy-1-adamantyl-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

Safety

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

RELATED PRODUCTS

(2S)-2-(Adamantan-1-yl)-2-((tert-butoxycarbonyl)amino)aceticacid
361441-97-6

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)-
1564265-98-0

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)-
1564265-94-6

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)-
1564265-96-8

Saxagliptin Impurity 15
1496712-39-0