95%

CAS NO.：

Empirical Formula: C10H10ClIN4

Molecular Weight: 348.57

MDL number: MFCD28387043

PRODUCT Properties

• Boiling point: 469.8±40.0 °C(Predicted)
• Density: 1.86±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C, sealed storage, away from moisture and light
• pka: -3.22±0.10(Predicted)
• Appearance: White to yellow Solid
• InChI: InChI=1S/C10H10ClIN4/c1-6(2)16-5-7(9(12)15-16)8-3-4-13-10(11)14-8/h3-6H,1-2H3
• InChIKey: NVQXUVPDZGMTOH-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC=CC(C2=CN(C(C)C)N=C2I)=N1

Description and Uses

2-chloro-4-[3-iodo-1-(1-Methylethyl)-1H-pyrazol-4-yl]-PyriMidine can be used as the intermediate of encorafenib.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H317-H411-H303-H401
• Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P501-P312