Calicheamicin , ≥98% , 108212-75-5

CAS NO.：108212-75-5

Empirical Formula: C55H74IN3O21S4

Molecular Weight: 1368.34

MDL number:

PRODUCT Properties

• alpha: D26 -124° (c = 0.98%, EtOH)
• Density: 1.57±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMSO : ≥ 100 mg/mL (73.08 mM);Water : < 0.1 mg/mL (insoluble)
• form: Solid
• pka: 7.13±0.60(Predicted)
• color: White to yellow
• InChIKey: HXCHCVDVKSCDHU-PENQSKQENA-N

Description and Uses

Calicheamicin gamma1 is an enediyne antitumor antibiotic that binds with DNA in the minor groove and is derived from the bacterium Micromonospora echinospora.

Calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, The main component is calicheamicin γ1. It has strong anti-Gram-positive bacteria activity and anti-tumor effect.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H341-H372-H361-H302
• Precautionary statements: P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501-P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501