M2086635
Dofequidar? , 98% , 129716-58-1
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB893.60 | In Stock |
|
| 10mg | RMB1422.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 720.8±60.0 °C(Predicted) |
| Density | 1.228 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 13.94±0.20(Predicted) |
| color | White to off-white |
Description and Uses
Dofequidar (MS-209 free base) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect[1][2].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
