M3329935
IcotinibHydrochloride , ≥99% , 1204313-51-8
CAS NO.：1204313-51-8
Empirical Formula: C22H22ClN3O4
Molecular Weight: 427.89
MDL number: MFCD22124500
EINECS: 1592732-453-0
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1185.60 | In Stock |
|
| 10mg | RMB2179.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| color | White to off-white |
| InChI | InChI=1S/C22H21N3O4.ClH/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20;/h1,3-5,12-15H,6-11H2,(H,23,24,25);1H |
| InChIKey | PNNGXMJMUUJHAV-UHFFFAOYSA-N |
| SMILES | N(C1C=CC=C(C#C)C=1)C1=NC=NC2C=C3OCCOCCOCCOC3=CC1=2.Cl |
Description and Uses
Icotinib Hydrochloride (BPI-2009) is a potent and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
