BIS(DIMETHYLAMINO)METHYLSILANE , 96% , 22705-33-5

CAS NO.：22705-33-5

Empirical Formula: C5H16N2Si

Molecular Weight: 132.28

MDL number: MFCD00048007

EINECS: 245-163-0

PRODUCT Properties

• Melting point: <0°C
• Boiling point: 112 °C
• Density: 0.798 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.414
• Flash point: -3°C
• pka: 10.24±0.70(Predicted)
• Specific Gravity: 0.798
• Hydrolytic Sensitivity: 9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required
• InChI: InChI=1S/C5H16N2Si/c1-6(2)8(5)7(3)4/h8H,1-5H3
• InChIKey: VBYLGQXERITIBP-UHFFFAOYSA-N
• SMILES: [SiH](C)(N(C)C)N(C)C
• EPA Substance Registry System: Silanediamine, N,N,N',N',1-pentamethyl- (22705-33-5)

Description and Uses

Bis(dimethylamino)methylsilane is used as a reagent in the pharmaceutical industry, primarily in silanation reactions.

Bis(dimethylamino)methylsilane can be used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups.

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H225-H314
• Precautionary statements: P210-P280-P305+P351+P338-P310
• Hazard Codes: F,C
• Risk Statements: 11-34
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 3
• F: 10-21
• TSCA: Yes