M4027035
MM-102 , 99% , 1417329-24-8
| Pack Size | Price | Stock | Quantity |
| 2mg | RMB1064.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20° C |
| solubility | insoluble in H2O; ≥22.6 mg/mL in EtOH; ≥67 mg/mL in DMSO |
| form | Powder |
| pka | 12.90±0.20(Predicted) |
| color | White to off-white |
| InChIKey | RZKSQRIPRKWVBU-MHZLTWQESA-N |
| SMILES | C1(NC(=O)[C@@H](NC(=O)C(CC)(NC(=O)C(C)C)CC)CCCNC(N)=N)(C(NC(C2=CC=C(F)C=C2)C2=CC=C(F)C=C2)=O)CCCC1 |
Description and Uses
MM-102 is a small molecule WDR5/MLL1 protein-protein interaction inhibitor. MM-102 in bone marrow cells transduced with MLL1-AF9 fusion construct decreases the expression of HoxA9 and Meis-1, two critical MLL1 target genes in MLL1 fusion protein mediated leukemogenesis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
