M4027435
MK-2048 , 99% , 869901-69-9
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB691.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.55 |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO > 10 mM |
| form | Powder |
| pka | 6.30±0.40(Predicted) |
| color | Light yellow to yellow |
Description and Uses
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
