M4278153
Nalmefene , 98% , 55096-26-9
Synonym(s):
(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB1120.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 182-185?C |
| Boiling point: | 507.9±50.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | pKa 7.63(H2O) (Uncertain) |
| color | White to Off-White |
| InChI | 1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1 |
| InChIKey | WJBLNOPPDWQMCH-MBPVOVBZSA-N |
| SMILES | Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=C)CC[C@@]35O)CC6CC6 |
| CAS DataBase Reference | 55096-26-9 |
| NIST Chemistry Reference | Nalmefene(55096-26-9) |
Description and Uses
Nalmefene is a 6-methylene analogue of naltrexone. It is a pure opioid receptor antagonist and has a high affinity for the κ-opioid receptor. Nalmefene has a long duration of action and is used in oral and parenteral formulations.
opioid antagonists therapeutic for alcohol dependence
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| target organs | Central nervous system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Chronic 1 STOT SE 3 |
| Hazardous Substances Data | 55096-26-9(Hazardous Substances Data) |
