M5068635
PSI-7976? , ≥98% , 1190308-01-0
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB14400.00 | In Stock |
|
| 5mg | RMB33600.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 76-82°C |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) |
| pka | 9.39±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | TTZHDVOVKQGIBA-YBSJRAAASA-N |
Description and Uses
Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
