Terlipressin , >99% , 14636-12-5
CAS NO.：14636-12-5
Empirical Formula: C52H74N16O15S2
Molecular Weight: 1227.37
MDL number: MFCD00155450
EINECS: 238-680-8
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB850.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >170°C (dec.) |
| Boiling point: | 1824.0±65.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.90±0.15(Predicted) |
| form | Solid |
| color | White |
| Sequence | Gly-Gly-Gly-c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2，(Disulfide bridge: Cys-Cys) |
| InChIKey | BENFXAYNYRLAIU-ITQMCZIINA-N |
| CAS DataBase Reference | 14636-12-5(CAS DataBase Reference) |
Description and Uses
Terlipressin acetate is a novel synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. After the action of aminopeptidase in the body, after removing the three glycyl residues at its N-terminus, it slowly "releases" the active lysine vasopressin. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.
Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It is used norepinephrine-resistant septic shock and hepatorenal syndrome. It is also used in the treatment of acute variceal bleeding. Terlipressin Acetate 1 mg solution for injection is used for the treatment of: bleeding from dilated (widening) veins in the food pipe leading to your stomach (called bleeding oesophageal varices).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H332 |
| Precautionary statements | P261-P271-P304+P340-P312 |
| HS Code | 3504009000 |
