Home Categories GSK-3βinhibitor1
M7159858

GSK-3βinhibitor1 , ≥98% , 187325-53-7

CAS NO.:187325-53-7

Empirical Formula: C14H10N2O

Molecular Weight: 222.24

MDL number:

Pack Size Price Stock Quantity
5g RMB1600.00 In Stock
25g RMB5600.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 457.2±45.0 °C(Predicted)
Density  1.291±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO
pka 12.34±0.20(Predicted)
form  Solid
color  Yellow to orange
InChI InChI=1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-
InChIKey YKQONSWBHGBDSB-XFXZXTDPSA-N
SMILES N1C2=C(C=CC=C2)/C(=C/C2=NC=CC=C2)/C1=O

Description and Uses

GSK-3β inhibitor 1 (compound 3a) inhibits GSK-3β with an IC50 of 4.19 nM. GSK-3β inhibitor 1 demonstrates high antidiabetic efficacy in obese Streptozotocin (HY-13753)-treated rats[1].