M7492358
D-threo-PPMPhydrochloride , ≥98% , 139889-65-9
Synonym(s):
1R,2R-(+)-1-phenyl-2-palmitoylamino-3-N-morpholine-1-propanol
CAS NO.：139889-65-9
Empirical Formula: C29H51ClN2O3
Molecular Weight: 511.19
MDL number: MFCD08703035
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB2620.00 | In Stock |
|
| 10mg | RMB4732.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | Ethanol: Soluble,Methanol: Soluble |
| form | A solid |
| color | White to off-white |
Description and Uses
D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor., It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growth in vitro at 20 μM and significantly inhibits DNA synthesis at 3 μM. [Matreya, LLC. Catalog No. 1865]
D-threo-PPMP hydrochloride is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP hydrochloride can block karyokinesis and reduce cyst production[1][2].