(?)-Voacangarine , 98% , 545-84-6

CAS NO.：545-84-6

Empirical Formula: C22H28N2O4

Molecular Weight: 384.47

MDL number:

PRODUCT Properties

• Melting point: 112-114 °C
• Boiling point: 542.9±50.0 °C(Predicted)
• Density: 1.32±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml
• form: A crystalline solid
• pka: 14.94±0.20(Predicted)

Description and Uses

(?)-Voacangarine is an indole alkaloid, which exhibits cytotoxic effects against cancer cells HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 of 5~20 mg/mL. (?)-Voacangarine inhibits the cultivation of Saccharomyces cerevisiae wildtype and repair-deficient mutants[1][2].