Celecoxib-d7 , 98% , 544686-21-7
CAS NO.：544686-21-7
Empirical Formula: C17H7D7F3N3O2S
Molecular Weight: 388.42
MDL number: MFCD08063418
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB3057.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | DMSO: 76 mg/ml,Ethanol: 33 mg/ml |
| form | A solid |
| color | Off-white to gray |
Description and Uses
Celecoxib-d7 is intended for use as an internal standard for the quantification of celecoxib by GC- or LC-MS. Celecoxib is a selective inhibitor of COX-2 (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). It displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of COX-2 inhibition. Formulations containing celecoxib have been used in the treatment of inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial anti-inflammatory drugs, however, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events.
Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.
Safety
| Symbol(GHS) |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H360-H400-H410 |
| Precautionary statements | P201-P202-P273-P280-P308+P313-P391-P405-P501 |
