CAY10443((S)-Indan-1-yl3,4-dichlorobenzylcarbamate) , 98% , 582314-48-5
CAS NO.：582314-48-5
Empirical Formula: C17H15Cl2NO2
Molecular Weight: 336.21
MDL number: MFCD08062128
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB743.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 495.6±45.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 11.15±0.46(Predicted) |
Description and Uses
Apoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 |