M8133047
Norfluoxetinehydrochloride(Desmethylfluoxetine) , 98% , 57226-68-3
CAS NO.:57226-68-3
Empirical Formula: C16H17ClF3NO
Molecular Weight: 331.76
MDL number: MFCD01321043
Pack Size | Price | Stock | Quantity |
1mg | RMB848.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
storage temp. | -20°C |
solubility | H2O: >4 mg/mL |
form | solid |
color | yellow |
Water Solubility | H2O: >4mg/mL DMSO: >5mg/mL |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Description and Uses
Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewater effluent.
Norfluoxetine Hydrochloride is a metabolite of Fluoxetine (F597100), a selective serotonin reuptake inhibitor which is used as an antidepressant.
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P261-P280-P305+P351+P338 |
WGK Germany | 3 |