Afoxolaner , 98% , 1093861-60-9
CAS NO.：1093861-60-9
Empirical Formula: C26H17ClF9N3O3
Molecular Weight: 625.87
MDL number: MFCD30533411
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB3243.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Density | 1.53±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: ≥ 250 mg/mL (399.44 mM) |
| form | A crystalline solid |
| pka | 12.45±0.46(Predicted) |
| color | White to off-white |
| InChIKey | OXDDDHGGRFRLEE-UHFFFAOYSA-N |
| SMILES | C1(C(NCC(=O)NCC(F)(F)F)=O)=C2C(C=CC=C2)=C(C2CC(C3=CC(C(F)(F)F)=CC(Cl)=C3)(C(F)(F)F)ON=2)C=C1 |
Description and Uses
Afoxolaner is an insecticide and acaricide belonging to the isoxazoline family. Afoxolaner acts at ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes.
Afoxolaner (brand name NexGard®) is used to treat and control flea and tick infestations in dogs. After being ingested by a dog, afoxolaner is distributed throughout the dog's body. When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.
Safety
| Symbol(GHS) |   GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H410-H361d |
| Precautionary statements | P273-P391-P501 |
