M8995734
Aztreonam , 98% , 78110-38-0
Synonym(s):
[2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-propanoic acid;Aztreonam
CAS NO.：78110-38-0
Empirical Formula: C13H17N5O8S2
Molecular Weight: 435.43
MDL number: MFCD00072145
EINECS: 278-839-9
| Pack Size | Price | Stock | Quantity |
| 1g | RMB101.60 | In Stock |
|
| 5g | RMB260.00 | In Stock |
|
| 25g | RMB756.80 | In Stock |
|
| 100g | RMB2320.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 227°C |
| Density | 1.83 |
| refractive index | 1.6460 (estimate) |
| storage temp. | room temp |
| solubility | DMSO (Slightly), Water (Slightly, Heated, Sonicated) |
| form | solid |
| pka | pKa -0.7(H2O t=RT Iundened) (Uncertain);2.75(H3O t=RT Iundened) (Uncertain);3.91(H4O t=RT Iundened) (Uncertain) |
| color | white to beige |
| Water Solubility | Soluble in DMF/water (1:1) at 50 mg/ml |
| Merck | 14,925 |
| Major Application | forensics and toxicology pharmaceutical (small molecule) veterinary |
| InChIKey | WZPBZJONDBGPKJ-VEHQQRBSSA-N |
| SMILES | C(O)(=O)C(O/N=C(/C1=CSC(N)=N1)\C(N[C@@H]1C(=O)N(S(O)(=O)=O)[C@H]1C)=O)(C)C |
| CAS DataBase Reference | 78110-38-0(CAS DataBase Reference) |
Description and Uses
Aztreonam is the first member of the monobactam class of antibiotics to be introduced into the world market. It possesses high β-lactamase stability and moderately good activity against gram negative aerobes such as E. coli, S. marcescens, -9 Proteus Providencia, Salmonella, g. influenzae, E. gonorrhea, and &. pneumonia. While somewhat less potent against Pseudomonas aeruginosa, it is nonetheless one of the better β-lactams against this species. It has poor activity against gram positive organisms.
The first totally synthetic monocyclic lactam antibiotic
Safety
| Symbol(GHS) |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H400-H334 |
| Precautionary statements | P273-P391-P501-P261-P285-P304+P341-P342+P311-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 2 |
| RTECS | UA2451400 |
| HS Code | 29419000 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | TDLo ivn-rat: 1100 mg/kg (7-17D preg):TER NKRZAZ33(Suppl 1),203,85 |
