M9417834
Ascomycin , Analysis of control products,> 90% , 11011-38-4
Synonym(s):
Aag;CGTHBA;nitrogen permease regulator-like 3 (S. cerevisiae)
CAS NO.：11011-38-4
Empirical Formula: C43H69NO12
Molecular Weight: 792.01
MDL number: MFCD06198665
EINECS: 658-052-0
| Pack Size | Price | Stock | Quantity |
| 20mg | RMB416.00 | In Stock |
|
| 100mg | RMB1504.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 158 - 161°C |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming). |
| form | White crystalline solid |
| color | White |
| biological source | goat |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
Description and Uses
Ascomycin (11011-38-4) is an analog of FK-506 (Cat.# 10-1103). Potent immunosuppressant1. Binds to FKBP122 and inhibits calcineurin and NFAT. Ascomycin displays anti-inflammatory effects in skin diseases3. Cell permeable and active in vivo.
A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases.
Safety
| Symbol(GHS) |   GHS08,GHS07 |
| Signal word | Warning |
| Hazard statements | H351-H413-H361-H302 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501 |
| RTECS | CI7570000 |
