S054879
6-Chloroacetyl-1,4-benzodioxane , 97% , 93439-37-3
| Pack Size | Price | Stock | Quantity |
| 25g | RMB2839.02 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 137-140 °C(lit.) |
| InChI | 1S/C10H9ClO3/c11-6-8(12)7-1-2-9-10(5-7)14-4-3-13-9/h1-2,5H,3-4,6H2 |
| InChIKey | ILEYSCVQRULQKW-UHFFFAOYSA-N |
| SMILES | ClCC(=O)c1ccc2OCCOc2c1 |
Description and Uses
6-Chloroacetyl-1,4-benzodioxane was used as an intermediate for the preparation of eliglustat hemitartrate and its intermediates. Eliglustat hemitartrate is a specific, potent, and orally active glucosylceramide synthase inhibitor with an IC50 of 24 nM.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
