2-(Diphenylphosphino)terephthalicacid1-methyl4-pentafluorophenyldiester , 97%

Synonym(s):
1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate

CAS NO.：

Empirical Formula: C27H16F5O4P

Molecular Weight: 530.379

MDL number: MFCD09265125

PRODUCT Properties

• Melting point: 109-111 °C
• storage temp.: -20°C

Description and Uses

• Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules.
• The amine functionalized molecule first reacts with the phosphine through the activated pentafluorophenyl ester.The azide-molecule is then reacted with the newly labeled phosphine to form the iminophosphorane, and the aza-ylide is subsequently captured by the methyl ester to yield the covalent conjugated product.

The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method