S1952716
≥90%(LC/MS-ELSD) , 91893-83-3
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB2361.02 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 602.6±55.0 °C(Predicted) |
| Density | 1.055±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 30 mg/ml |
| form | A film |
| pka | 5.00±0.19(Predicted) |
| Major Application | metabolomics vitamins, nutraceuticals, and natural products |
| InChIKey | QOFWRHWADNWKSU-LRXIOGKNSA-N |
| SMILES | C\C(CC\C=C(/C)C(O)=O)=C/CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1 |
Description and Uses
Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora. It inhibits IL-1β-induced microsomal prostaglandin E2 synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM. It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM.
Garcinoic Acid displays anti-angiogenic activity as well as anti-oxidative activity in animals.
Safety
| Symbol(GHS) |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301-H410 |
| Precautionary statements | P273-P301+P310+P330 |
| Hazard Codes | T,N |
| Risk Statements | 25-50 |
| Safety Statements | 61 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 |
