S3206251
Anti-BCR(Ab-177)antibodyproducedinrabbit , affinityisolatedantibody
Synonym(s):
Anti-ALL antibody produced in rabbit;Anti-BCR1 antibody produced in rabbit;Anti-BCR-ABL1 antibody produced in rabbit;Anti-breakpoint cluster region antibody produced in rabbit;Anti-CML antibody produced in rabbit
| Pack Size | Price | Stock | Quantity |
| 100μG | RMB3465.74 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | -20°C |
| form | buffered aqueous solution |
| biological source | rabbit |
Description and Uses
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac.
Safety
| WGK Germany | nwg |
| Storage Class | 10 - Combustible liquids |