S452278
Methyl trans-3-(4-methoxyphenyl)glycidate , 97% , 42245-42-1
CAS NO.：42245-42-1
Empirical Formula: C11H12O4
Molecular Weight: 208.21
MDL number: MFCD00012316
EINECS: 255-735-1
| Pack Size | Price | Stock | Quantity |
| 5g | RMB656.05 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 69-71 °C(lit.) |
| solubility | Dichloromethane; Chloroform; Ethyl Acetate; DMSO; |
| form | Solid |
| color | White |
| InChI | 1S/C11H12O4/c1-13-8-5-3-7(4-6-8)9-10(15-9)11(12)14-2/h3-6,9-10H,1-2H3/t9-,10+/m1/s1 |
| InChIKey | CVZUMGUZDAWOGA-ZJUUUORDSA-N |
| SMILES | COC(=O)[C@H]1O[C@@H]1c2ccc(OC)cc2 |
| EPA Substance Registry System | Oxiranecarboxylic acid, 3-(4-methoxyphenyl)-, methyl ester (42245-42-1) |
Description and Uses
Methyl 2,3 epoXY-3-(4-methoxyphenyl)propionate is an intermediate product in the synthesis of diltiazem hydrochloride. Contact dermatitis was observed in several laboratory technicians.
Methyl trans-3-(4-Methoxyphenyl)glycidate is an intermediate used in the synthesis of Clentiazem (C573035), which is a benzothiazepine-like calcium antagonists; Enhances endothelium-dependent coronary artery relaxation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
