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CAS NO.：

Empirical Formula: C3H3F3O

Molecular Weight: 112.05

MDL number: MFCD08276876

PRODUCT Properties

• Boiling point: 25-32 °C
• Density: 1.294 g/mL at 25 °C
• refractive index: n20/D <1.300
• Flash point: -15 °F
• storage temp.: 2-8°C
• form: liquid
• color: Clear
• InChI: InChI=1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1
• InChIKey: AQZRARFZZMGLHL-UWTATZPHSA-N
• SMILES: O1C[C@@H]1C(F)(F)F

Description and Uses

(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:

• Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
• (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

Safety

• Symbol(GHS): GHS02
• Signal word: Danger
• Hazard statements: H224
• Precautionary statements: P210-P403+P233
• Hazard Codes: F+
• Risk Statements: 12
• Safety Statements: 3
• RIDADR: UN 1993 3/PG 1
• WGK Germany: 3
• HS Code: 2910900090