Z-L-Phe chloromethyl ketone , 98% , 26049-94-5

Synonym(s):
N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone;NSC 251810;SL-01;ZPCK

CAS NO.：26049-94-5

Empirical Formula: C18H18ClNO3

Molecular Weight: 331.79

MDL number: MFCD00037114

EINECS: 247-432-8

PRODUCT Properties

• Melting point: 107-108 °C(lit.)
• Boiling point: 503.1±50.0 °C(Predicted)
• Density: 1.1630 (rough estimate)
• refractive index: 1.6470 (estimate)
• storage temp.: -20°C
• solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
• form: solid
• pka: 10.74±0.46(Predicted)
• color: White
• optical activity: [α]23/D +30°, c = 1 in chloroform
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
• Major Application: peptide synthesis
• InChI: 1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1
• InChIKey: OYHLRJGDELITAF-INIZCTEOSA-N
• SMILES: ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2
• CAS DataBase Reference: 26049-94-5
• EPA Substance Registry System: Benzyl [(1S)-3-chloro-2-oxo-1-benzylpropyl]carbamate (26049-94-5)

Description and Uses

SL-01 (26049-94-5) inhibits the p53-MDM2 interaction (20 μM). Has also been shown to inhibit bovine chymotrypsin A-γ.

Enzyme inhibitor.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
• PPE: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• Hazard Codes: C
• Risk Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• TSCA: TSCA listed
• HS Code: 29225000
• Storage Class: 8A - Combustible corrosive hazardous materials
• Hazard Classifications: Skin Corr. 1B