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S7869448

DL-Tartaricacid , Vetec ,reagentgrade,99% , 133-37-9

Synonym(s):
Carboxyl sulfonyl fluoride alkyne;Probe building block

CAS NO.:133-37-9

Empirical Formula: C12H13FO4SSi

Molecular Weight: 300.38

MDL number:

Pack Size Price Stock Quantity
500g RMB173.04 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 402.9±45.0 °C(Predicted)
Density  1.32±0.1 g/cm3(Predicted)
storage temp.  -20°C
form  solid
pka 3.25±0.10(Predicted)
InChIKey CNXMDAYMSVWYAS-UHFFFAOYSA-N
SMILES O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

Description and Uses

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H242-H315-H319
Precautionary statements  P210-P235-P302+P352-P305+P351+P338-P370+P378-P403
WGK Germany  WGK 3
Storage Class 5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications Eye Irrit. 2
Self-react. C
Skin Irrit. 2