≥90.0%(HPLC) , 652154-13-7

CAS NO.：652154-13-7

Empirical Formula: C9H14N3Na2O14P3

Molecular Weight: 527.12

MDL number: MFCD00150807

EINECS: 252-849-3

PRODUCT Properties

• Flash point: >230 °F
• storage temp.: -20°C
• solubility: H2O: soluble50mg/mL, clear, colorless
• form: A crystalline solid
• Water Solubility: H2O: 50mg/mL, clear, colorless
• BRN: 3582735
• InChIKey: IJMSOWKYYIROGP-LLWADOMFSA-L
• SMILES: O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

Description and Uses

Cytidine 5''-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.

Cytidine 5′-triphosphate disodium salt hydrate has been used:

• in the oligonucleotide synthesis for silver nanoclusters?interaction studies
• as an anion source for fluorescence emission and titration curve-analysis of hypocrellin A-zinc(II) complex
• in fluorescence emission experiments of copper(II)–2,6-bis(2-benzimidazolyl)pyridine complex

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• WGK Germany: 3
• F: 10-21
• Storage Class: 11 - Combustible Solids