AtorvastatinRelatedCompoundA , UnitedStatesPharmacopeia(USP)ReferenceStandard , 433289-83-9

Synonym(s):
(βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt

CAS NO.：433289-83-9

Empirical Formula: C33H35CaN2O5+

Molecular Weight: 579.719

MDL number: MFCD11977955

PRODUCT Properties

• Melting point: 150℃ (decomposition)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• InChIKey: HBFCHKRJRYFUBH-QXFSHCJSNA-M
• SMILES: c1(-c2ccccc2)c(C(=O)Nc2ccccc2)c(C(C)C)[n](CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccccc1.[Ca+2] |&1:24,27,r|

Description and Uses

Desfluoro Atorvastatin is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26
• HS Code: 2933997500