4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate , ≥80% , 51023-76-8

Synonym(s):
Disodium 4-acetamido-4′-isothiocyanato-stilben-2,2′-disulfonate;SITS

CAS NO.：51023-76-8

Empirical Formula: C17H12N2Na2O7S3

Molecular Weight: 498.46

MDL number: MFCD00007485

EINECS: 256-919-4

PRODUCT Properties

• Melting point: >300°C (dec.)
• storage temp.: -20°C
• solubility: Soluble in water, methanol, dimethyl sulfoxide
• form: powder
• color: Yellow or tan-yellow
• Appearance: Solid Powder
• λmax: 336 nm
• BRN: 9177451
• Stability: Temperature sensitive - recommended storage at -20oC
• Biological Applications: Chloride channel blockers; anion transport inhibitors; treating cancer,glaucoma,heart diseases,viral diseases
• InChIKey: NPAWAMRXPHRVQY-WTVBWJGASA-L
• SMILES: [Na+].[Na+].CC(=O)Nc1ccc(\C=C\c2ccc(cc2S([O-])(=O)=O)N=C=S)c(c1)S([O-])(=O)=O
• CAS DataBase Reference: 51023-76-8(CAS DataBase Reference)
• EPA Substance Registry System: Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt (51023-76-8)

Description and Uses

SITS is an amine-reactive fluorescent probe for studying ion transporter.

Fluorescent marker for membranes; inhibits anion permeability of membranes. Also inactivates Na,K-ATPase, by covalent modification of a specific Lys residue.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H319-H334-H335
• Precautionary statements: P301+P312+P330-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-42
• Safety Statements: 22-26-36/37
• WGK Germany: 3
• F: 8-10-21
• TSCA: TSCA listed
• HS Code: 2930909899
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral; Eye Irrit. 2; Resp. Sens. 1; Skin Irrit. 2; STOT SE 3