S9106114
≥98%(HPLC) , 629664-81-9
Synonym(s):
3-(3,4-Difluoro-benzoyl)-1,1-dimethylene-1,2,3,6-tetrahydro-azepino [4,5-b]indole-5-carboxylic acid isopropyl ester;3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethyl-azepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester;Turofexorate isopropyl
CAS NO.：629664-81-9
Empirical Formula: C25H24F2N2O3
Molecular Weight: 438.47
MDL number: MFCD13181507
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1033.47 | In Stock |
|
| 25mg | RMB4165.50 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 617.3±55.0 °C(Predicted) |
| Density | 1.275 |
| storage temp. | room temp |
| solubility | DMSO : 25 mg/mL (57.02 mM; Need ultrasonic) |
| form | powder |
| pka | 16.49±0.60(Predicted) |
| color | white to beige |
| InChI | InChI=1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3 |
| InChIKey | INASOKQDNHHMRE-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2)C2C(C)(C)CN(C(=O)C3=CC=C(F)C(F)=C3)C=C(C(OC(C)C)=O)C1=2 |
Description and Uses
Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
