≥95%(HPLC) , 128719-90-4

Synonym(s):
(5Z)-7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid

CAS NO.：128719-90-4

Empirical Formula: C23H29IO5

Molecular Weight: 512.38

MDL number: MFCD00084824

EINECS: 200-578-6

PRODUCT Properties

• Boiling point: 634.5±55.0 °C(Predicted)
• Density: 1.483±0.06 g/cm3(Predicted)
• Flash point: 14℃
• storage temp.: -20°C
• solubility: DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS (pH 7.2): 3 mg/ml
• pka: 4.76±0.10(Predicted)
• form: solution
• color: colorless to faint yellow

Description and Uses

I-BOP is an agonist for thromboxane A2 receptor (TP) with a KD of 0.61 nM. I-BOP promotes proliferation through activation of PI3K pathway in vascular smooth muscle[1]. I-BOP dose-dependently biphasicly affects the excitatory postsynaptic potential (e.p.s.p.) in hippocampal neurons[2].

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319
• Precautionary statements: P210-P305+P351+P338
• Hazard Codes: F
• Risk Statements: 11
• Safety Statements: 7-16
• RIDADR: UN1170 - class 3 - PG 2 - Ethanol, solution
• WGK Germany: 2