forsynthesis , 553-26-4
Synonym(s):
11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-D4;11β,17α,21-Trihydroxypregn-4-ene-3,20-dione-d4 (9,11,12,12-d4);17-Hydroxycorticosterone-9,11,12,12-d4;17-Hydroxycorticosterone-D4;4-Pregnene-11β,17α,21-triol-3,20-dione-D4
CAS NO.：553-26-4
Empirical Formula: C21H26D4O4
Molecular Weight: 350.49
MDL number: MFCD00144010
EINECS: 694-327-1
| Pack Size | Price | Stock | Quantity |
| 10g | RMB259.96 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 211-214 °C |
| Flash point: | 9℃ |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Heated), Water |
| form | Solid |
| color | White to Off-White |
| Appearance | white powder |
| CAS Number Unlabeled | 50-23-7 |
Description and Uses
Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.
Anti-inflammatory hormone
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| Hazard Codes | Xn,T,F |
| Risk Statements | 63-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-16-7 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
