T8587130
Ethyl 1,3-Dithiolane-2-carboxylate , >97.0%(GC) , 20461-99-8
Synonym(s):
Glyoxylic acid ethyl ester ethylene mercaptal
CAS NO.：20461-99-8
Empirical Formula: C6H10O2S2
Molecular Weight: 178.27
MDL number: MFCD00005411
EINECS: 243-837-9
| Pack Size | Price | Stock | Quantity |
| 5g | RMB580.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 85 °C/0.1 mmHg (lit.) |
| Density | 1.249 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear light yellow |
| Specific Gravity | 1.249 |
| BRN | 118157 |
| InChI | 1S/C6H10O2S2/c1-2-8-5(7)6-9-3-4-10-6/h6H,2-4H2,1H3 |
| InChIKey | OMCSHTHLIQOHDD-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C1SCCS1 |
| CAS DataBase Reference | 20461-99-8(CAS DataBase Reference) |
Description and Uses
Ethyl 1,3-dithiolane-2-carboxylate is an α-keto acid equivalent. It participates in the conjugate additions to enones. It is a bulky equivalent of acetate undergoing syn-selective aldol reactions. Anion derived from ethyl 1,3-dithiolane-2-carboxylate participates as nucleophile during the total synthesis of the corynanthe alkaloid dihydrocorynantheol and the formal syntheses of the indole alkaloids tacamonine, rhynchophylline and hirsutine. It also participates in the conjugate addition of enolates to phenylglycinol-derived α,β-unsaturated δ-lactams.
