T9841330
Protopine , >98.0%(GC) , 130-86-9
Synonym(s):
4,6,7,14-Tetrahydro-5-methylbis[1,3]benzodioxolo[4,5-c:5′,6′-g]azecin-13(5H)-one
CAS NO.：130-86-9
Empirical Formula: C20H19NO5
Molecular Weight: 353.37
MDL number: MFCD00022322
EINECS: 204-999-6
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB380.00 | In Stock |
|
| 25mg | RMB1276.00 | In Stock |
|
| 100mg | RMB3192.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 203-205?C |
| Boiling point: | 486.8°C (rough estimate) |
| Density | 1.399 (calc) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| Water Solubility | Insoluble in water |
| solubility | DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic) |
| pka | 7.86±0.20(Predicted) |
| form | powder to crystal |
| color | White to Light gray to Light yellow |
| InChI | InChI=1S/C20H22NO5/c1-25-11-23-17-5-4-13-2-3-14-9-19-18(24-12-26(19)22)8-15(14)6-7-21-10-16(13)20(17)25/h2-5,8,16,21H,6-7,9-12H2,1H3/b13-2-,14-3- |
| InChIKey | JVVZZYVMOGCQIP-JAIUMMMNSA-N |
| SMILES | N1CCC2=CC3OCO(=O)C=3CC2=CC=C2C=CC3OCO(C)C=3C2C1 |c:14,t:16| |
| LogP | 3.760 (est) |
| NIST Chemistry Reference | Protopine(130-86-9) |
Description and Uses
Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312+P330-P501 |
| Safety Statements | 24/25 |
| RIDADR | 1544 |
| RTECS | VS2800000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29391900 |
| Hazardous Substances Data | 130-86-9(Hazardous Substances Data) |
| Toxicity | guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973. |
