4-Aminoindole , 97% , 5192-23-4

Synonym(s):
(Indol-4-yl)amine;4-Indolamine

CAS NO.：5192-23-4

Empirical Formula: C8H8N2

Molecular Weight: 132.16

MDL number: MFCD01076559

EINECS: 621-202-0

PRODUCT Properties

• Melting point: 106-109 °C (lit.)
• Boiling point: 354.0±15.0 °C(Predicted)
• Density: 1.268±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: powder to crystal
• pka: 18.23±0.30(Predicted)
• color: White to Gray to Brown
• Water Solubility: Insoluble
• Sensitive: Air Sensitive
• BRN: 114919
• InChI: InChI=1S/C8H8N2/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5,10H,9H2
• InChIKey: LUNUNJFSHKSXGQ-UHFFFAOYSA-N
• SMILES: N1C2=C(C(N)=CC=C2)C=C1
• CAS DataBase Reference: 5192-23-4(CAS DataBase Reference)

Description and Uses

Reactant for preparation of:• ;Inhibitors of bacterial thymidylate synthase1• ;Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3• ;Protein kinase C θ (PKCθ) inhibitors4• ;Indolic non-peptidic HIV protease inhibitors5• ;Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6• ;Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7• ;11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibi

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-24/25
• WGK Germany: 3
• F: 8-10-34
• HazardClass: AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD
• HS Code: 29339990