Benzofuran-3(2H)-one , 98% , 7169-34-8

Synonym(s):
3-Coumaranone

CAS NO.：7169-34-8

Empirical Formula: C8H6O2

Molecular Weight: 134.13

MDL number: MFCD00051810

EINECS: 640-279-1

PRODUCT Properties

• Melting point: 101-103 °C
• Boiling point: 207.23°C (rough estimate)
• Density: 1.1603 (rough estimate)
• refractive index: 1.4800 (estimate)
• storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), DMSO (Slightly)
• form: Solid
• color: Yellow to Dark Yellow
• Water Solubility: Slightly miscible with water.
• Sensitive: Light Sensitive
• BRN: 115296
• InChI: InChI=1S/C8H6O2/c9-7-5-10-8-4-2-1-3-6(7)8/h1-4H,5H2
• InChIKey: MGKPCLNUSDGXGT-UHFFFAOYSA-N
• SMILES: O1C2=CC=CC=C2C(=O)C1
• CAS DataBase Reference: 7169-34-8(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-benzofuranone(7169-34-8)

Description and Uses

3-Coumaranone is used in the aurones, [2-benzylidenebenzofuran-3(2H)-ones] by reacting with appropriate aldehyde. It is involved in the condensation reaction with aldehydes in the presence of morpholine acetate to prepare substituted 2-(arylidene)benzofuran-3(ZH)-ones. In Horner-Wadsworth-Emmons reaction, it reacts with diethyl? cyanomethyl?phosphonate to give 3-(cyanomethyl)benzofurans, which is an intermediate in the synthesis of antihyperglycemic agents.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H332-H335
• Precautionary statements: P261-P280-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 22-24/25-36/37/39-26-36
• WGK Germany: 3
• F: 4.5-9
• Hazard Note: Irritant
• HS Code: 29329990