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A4661756

Fexofenadine , 98% , 83799-24-0

CAS NO.:83799-24-0

Empirical Formula: C32H39NO4

Molecular Weight: 501.66

MDL number: MFCD00871892

EINECS: 801-893-7

Pack Size Price Stock Quantity
1g RMB404.00 In Stock
5g RMB1399.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 218-220°C
Boiling point: 697.3±55.0 °C(Predicted)
Density  1.171±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  Methanol (Slightly, Heated, Sonicated)
form  Solid
pka 4.43±0.10(Predicted)
color  White to Off-White
BCS Class 1,3
LogP 2.81
CAS DataBase Reference 83799-24-0(CAS DataBase Reference)

Description and Uses

Fexofenadine, the carboxylic acid metabolite of terfenadine, is widely available. It accounts for the antihistaminic properties of terfenadine, which is very rapidly metabolized via CYP3A4-catalyzed processes. Members of the organic anion transporter protein family and the drug efflux transporter P-glycoprotein are involved in the disposition of fexofenadine. Fexofenadine does not have the antiarrhythmic side effects of terfenadine.

The active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.

Safety

Hazardous Substances Data 83799-24-0(Hazardous Substances Data)

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