Hordenine , Analysis of standard products, ≥99% , 539-15-1
Synonym(s):
N,N-Dimethyltyramine;p-Hydroxy-N,N-dimethylphenethylamine;2-(4-Hydroxyphenyl)-N,N-dimethylethylamine;4-(2-Dimethylaminoethyl)phenol;Anhaline
CAS NO.：539-15-1
Empirical Formula: C10H15NO
Molecular Weight: 165.23
MDL number: MFCD00051462
EINECS: 208-710-4
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB239.20 | In Stock |
|
| 1g | RMB7199.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 117-118° |
| Boiling point: | bp11 173° |
| Density | 1.0203 (rough estimate) |
| refractive index | 1.4820 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.05±0.26(Predicted) |
| color | Pale Yellow to Dark Beige |
| Merck | 14,4746 |
| BRN | 2207615 |
| LogP | 1.400 (est) |
| CAS DataBase Reference | 539-15-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 4-[2-(dimethylamino)ethyl]-(539-15-1) |
Description and Uses
Hordenine (Item No. 21626) is a naturally occurring alkaloid found in a variety of plants, most commonly germinated barley (Hordeum species) from which the name is derived, and is structurally classified as a phenethylamine. It is biosynthesized by the step-wise double methylation of tyramine . Hordenine binds to and activates the dopamine D2 receptor (Ki = 13 μM) but antagonizes D2 receptor β-arrestin recruitment. It inhibits tyrosinase activity and expression at concentrations ≥ 50 μM resulting in reduced melanin accumulation in human melanocytes. Hordenine is present in significant amounts in beer and can be measured in serum in the free form, for up to 2 hours, and the glucuronidated form, for up to 6 hours, after beer consumption. This product is intended for research and forensic applications.
Hordenine is suitable to study the effect of reed canary grass alkoloids on in vito digestibility. It is also suitable for use as a standard to identify endogenous hordenine in ungerminated and germinated barley by HPLC/diode array detection analysis. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36-43 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| HS Code | 29222990 |
