N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid , 99% , 68399-81-5

Synonym(s):
2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid;N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid

CAS NO.：68399-81-5

Empirical Formula: C7H17NO7S

Molecular Weight: 259.28

MDL number: MFCD00038352

EINECS: 269-993-8

PRODUCT Properties

• Melting point: 224-229 °C (dec.)
• Density: 1.07607 g/cm3(Temp: 25.00 °C)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• form: Powder
• color: Off-white to yellow
• pka: 7.6(at 25℃)
• PH Range: 7.0 - 8.2
• PH: 7.0-8.2
• Water Solubility: soluble
• Merck: 13,9148
• BRN: 2113949
• InChI: InChI=1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)
• InChIKey: RZQXOGQSPBYUKH-UHFFFAOYSA-N
• SMILES: C(S(O)(=O)=O)C(O)CNC(CO)(CO)CO
• CAS DataBase Reference: 68399-81-5(CAS DataBase Reference)
• EPA Substance Registry System: 1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (68399-81-5)

Description and Uses

TAPSO is a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research. It has a pKa value of 7.635 (I=0, 25°C) and can be used to make buffer solutions in the pH range 7.0-8.2. As an Good'buffer, TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides[1]. TAPSO can serve as good stabilizers for the globular protein BSA, in the aqueous solutions[2].The solubilities of TAPSO increase with increasing concentration of the salts (salting-in effect)[3].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• HS Code: 29221990