A7743458
ML-167 , 10mMinDMSO , 1285702-20-6
Synonym(s):
5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol;CID 44968231;NCGC00188654
CAS NO.：1285702-20-6
Empirical Formula: C19H17N3O3
Molecular Weight: 335.36
MDL number: MFCD27978379
EINECS: 808-432-9
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB445.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 531.8±45.0 °C(Predicted) |
| Density | 1.335±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 13.84±0.10(Predicted) |
| form | powder |
| color | off-white to gray to brown |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Description and Uses
ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50?= 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM).
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B[1].
