tert-Butyl (2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate , 97% , 1076199-21-7

CAS NO.：1076199-21-7

Empirical Formula: C13H26BrNO5

Molecular Weight: 356.25

MDL number: MFCD09840081

PRODUCT Properties

• Boiling point: 422.1±35.0 °C(Predicted)
• Density: 1.238±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 12.23±0.46(Predicted)
• form: Oil
• color: Yellow

Description and Uses

N-Boc-PEG3-bromide is a PEG linker containing a Boc protected amine and a bromide group. The protected amine can be deprotected under mild acidic conditions. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338