LN2042251
1346502-15-5
Pack Size | Price | Stock | Quantity |
1g | RMB10234.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 379.7±27.0 °C(Predicted) |
Density | 1.446±0.06 g/cm3(Predicted) |
pka | 3.39±0.10(Predicted) |
Description and Uses
Bromo-PEG3-CH2CO2H is a PEG linker containing a bromide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.
Br-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.