Home Categories 5-Ethynylpyrimidine-2,4(1H,3H)-dione
BD1101332

5-Ethynylpyrimidine-2,4(1H,3H)-dione , 98% , 59989-18-3

CAS NO.:59989-18-3

Empirical Formula: C6H4N2O2

Molecular Weight: 136.11

MDL number: MFCD00871973

Pack Size Price Stock Quantity
100mg RMB254.40 In Stock
250mg RMB432.00 In Stock
1g RMB1166.40 In Stock
5g RMB4082.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 320° (dec)
Density  1.527
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Soluble in DMSO
form  solid
pka 7.44±0.10(Predicted)
color  Yellow
λmax 284nm(MeOH)(lit.)
Merck  14,3584
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Description and Uses

Eniluracil (59989-18-3) is an irreversible dihydropyrimidine dehydrogenase (DPD) inhibitor.1-3? DPD is involved in the degradation of pyrimidine-based chemotherapeutic drugs such as 5-fluorouracil (5-FU).? Eniluracil has been used along with 5-FU to prolong circulating concentrations of the drug.

Potent inactivator of Dihydropyrimidine dehydrogenase (DPD).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.59.9500

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