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BD5279248

Trimetrexate , 98+% , 52128-35-5

CAS NO.:52128-35-5

Empirical Formula: C19H23N5O3

Molecular Weight: 369.42

MDL number:

Pack Size Price Stock Quantity
1mg RMB776.80 In Stock
5mg RMB1746.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 215-217 °C
Boiling point: 647.0±65.0 °C(Predicted)
Density  1.305±0.06 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  DMSO : ≥ 61.5 mg/mL (166.48 mM)
form  Solid
pka 8.09±0.30(Predicted)
color  Light yellow to green yellow

Description and Uses

Trimetrexate (TMQ) has been approved for the treatment of Pneumocystis carinii in patients with AIDS and also exhibits antiprotozoal activity against Trypanosoma cruzi . The drug is available as a single-ingredient medication, but it can be administered along with folinic acid in much the same way that methotrexate is administered with calcium leucovorin in cancer chemotherapy. Trimetrexate is a derivative of methotrexate.

Antineoplastic.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazardous Substances Data 52128-35-5(Hazardous Substances Data)

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