LN-164120
LOFEPRAMINE HYDROCHLORIDE , 95% , 26786-32-3
Synonym(s):
N-(4-Chlorobenzoylmethyl)-3-(10,11-dihydro-5h-dibenz[b,f]azepin-5-yl)-n-methylpropylamine hydrochloride
CAS NO.：26786-32-3
Empirical Formula: C26H28Cl2N2O
Molecular Weight: 455.42
MDL number: MFCD00941486
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 152-154° |
| Flash point: | 9℃ |
| storage temp. | 2-8°C |
| solubility | DMSO: ~24 mg/mL |
| form | solid |
| color | off-white |
| Major Application | pharmaceutical pharmaceutical small molecule |
| InChI | 1S/C26H27ClN2O.ClH/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29;/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3;1H |
| InChIKey | ZWZIQPOLMDPIQM-UHFFFAOYSA-N |
| SMILES | Cl[H].CN(CCCN1c2ccccc2CCc3ccccc13)CC(=O)c4ccc(Cl)cc4 |
Description and Uses
Monoamine reuptake inhibitor; tricyclic antidepressant.
Safety
| Symbol(GHS) |     GHS02,GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225-H290-H301+H311+H331-H370 |
| Precautionary statements | P210-P280-P302+P352+P312-P304+P340+P312-P370+P378-P403+P235 |
| Hazard Codes | Xn |
| Risk Statements | 22-37-53 |
| Safety Statements | 22-24/25-26-28-36/37/39-38 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | AM6485000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
| Toxicity | LD50 in mice, rats (mg/kg): >2500, >1000 orally; 920, >1000 i.p.; >1000, >1000 s.c. (Eriksoo, Rohte) |
