LN-242032
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER TRIETHYLAMMONIUM SALT , 99% by HPLC , 153660-04-9
Synonym(s):
Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt;Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt;Rp-8-CPT-cGMPS
CAS NO.：153660-04-9
Empirical Formula: C16H15ClN5O6PS2
Molecular Weight: 503.88
MDL number: MFCD01861936
Update time: 2023-04-23
PRODUCT Properties
| storage temp. | −20°C |
| solubility | H2O: 5 mg/mL |
| form | solid |
| color | white |
| Water Solubility | water: 0.5mg/mL DMSO: soluble |
Description and Uses
Rp-8-pCPT-cGMPS is a competitive inhibitor of cGMP-dependent protein kinase (PKG) (Ki=0.5 μM). Rp-8-pCPT-cGMPS has high lipid solubility and can more easily penetrate the cell membrane and reach sufficient concentration inside the cell to inhibit cGMP-dependent protein kinase. Rp-8-pCPT-cGMPS can be used to study the activity and function of cGMP-dependent protein kinase in platelets[1].
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
