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1400191-52-7

Synonym(s):
DBCO-sulfo-NHS ester;DBCO-sulfo-SE

CAS NO.:1400191-52-7

Empirical Formula: C25H23N2NaO8S

Molecular Weight: 534.51

MDL number: MFCD22572669

Pack Size Price Stock Quantity
1g RMB37693.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 240-260 °C
storage temp.  -20°C
form  Solid
color  Off-white to yellow
InChIKey NSZPURPXEZOXPC-UHFFFAOYSA-N
SMILES C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH]

Description and Uses

DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions.

Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.

Safety

WGK Germany  3

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